cobenfy
Pricing Information

Like many patients, knowing what you may pay for treatment can be a major concern. That’s why Bristol Myers Squibb is committed to helping you understand your out-of-pocket costs and possible resources that may help make them more affordable.

For additional information, COBENFY Cares™ provides resources to help patients who have been prescribed COBENFY understand their insurance coverage and find information on sources of financial support.

Please visit COBENFY.com or call COBENFY Cares™ 1-877-COBENFY (1-877-262-3639) 24 hours a day, 7 days a week.

The list price of COBENFY is $1,850 for 30 days.* Most patients will pay less.

If you have Medicaid

To find out if you qualify for Medicaid or to get more information about whether co-payments or other cost-sharing may apply in your state, please use this link to visit the Medicaid website or contact your state Medicaid program.

If you have Medicare

For COBENFY, your costs are determined by your pharmacy coverage such as Medicare Part D or Medicare Advantage (a.k.a., Part C), your coverage phase, and your income level. Use this link to learn about costs for Medicare drug coverage.

Your cost could be less if you are eligible for the Social Security Administration’s Extra Help program. If you qualify for Extra Help, COBENFY will cost you no more than $11.20.

You may automatically have extra help if you are:

  • Dual Eligible
  • Signed up for both Medicare and Medicaid
  • Older than 65 and on Medicaid
  • Getting Supplemental Security Income through the Social Security Administration
  • A member of a Medicare Savings Program

Visit https://www.ssa.gov/benefits/
medicare/prescriptionhelp/
for more information and to see if you qualify.

If you have commercial insurance

Eligible commercially insured patients may pay as little as $0 a month for COBENFY with the COBENFY Co-Pay Assistance Program.

Program enrollment opens October 25, 2024.

If you do not have insurance coverage

If you do not have coverage for COBENFY, you may pay the list price shown above, along with any additional pharmacy charges, less any available discounts, based on where you purchase your prescription medicine.

*As of October 2024, for a 30-day supply. List price is also known as wholesale acquisition cost, or WAC. WAC is the price at which pharmaceutical manufacturers sell their products to wholesalers or direct purchasers in the United States, not including prompt pay or other discounts, rebates, or reductions in price. Most people do not pay the list price for COBENFY.


What is Cobenfy (co-BEN-fee)?

COBENFY™ (xanomeline and trospium chloride) is a(n oral) prescription medicine used to treat schizophrenia in adults.

It is not known if COBENFY is safe and effective in children.

Select Important Safety Information

Do not take COBENFY if you:

  • have urinary retention problems that cause your bladder to not empty completely or not empty at all
  • have moderate or severe liver problems (impairment)
  • have gastric retention problems that cause your stomach to empty slowly
  • are allergic to COBENFY, xanomeline, or trospium chloride, or any of the ingredients in COBENFY.
  • have an eye problem called untreated narrow-angle glaucoma

IMPORTANT SAFETY INFORMATION

Do not take COBENFY if you:

  • have urinary retention problems that cause your bladder to not empty completely or not empty at all
  • have moderate or severe liver problems (impairment)
  • have gastric retention problems that cause your stomach to empty slowly
  • are allergic to COBENFY, xanomeline, or trospium chloride, or any of the ingredients in COBENFY
  • have an eye problem called untreated narrow-angle glaucoma

Before taking COBENFY, tell your healthcare provider about all of your medical conditions, including if you:

  • have an enlarged prostate, problems passing urine, or a blockage in your urinary bladder
  • have liver problems
  • have or have had gallstones or problems with your bile ducts or pancreas
  • have stomach or intestinal problems, including constipation, ulcerative colitis, slow emptying of your stomach, or myasthenia gravis
  • have an eye condition called narrow-angle glaucoma
  • have kidney problems
  • are pregnant or plan to become pregnant. It is not known if COBENFY may harm your unborn baby. Tell your healthcare provider if you become pregnant or think you are pregnant during treatment with COBENFY.
  • are breastfeeding or plan to breastfeed. It is not known if COBENFY passes into your breast milk or if it can harm your baby.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking COBENFY with certain other medicines may increase your risk of side effects from COBENFY or the other medicine and may affect the way COBENFY or the other medicine works. Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.

What should I avoid while taking COBENFY?

Do not drive, operate heavy machinery, or do other dangerous activities until you know how COBENFY affects you. COBENFY may cause dizziness, confusion, seeing or hearing things that are not real (hallucinations), and sleepiness.

COBENFY may cause serious side effects, including:

  • Problems with emptying your bladder (urinary retention). See “Do not take COBENFY if you:” COBENFY may cause your bladder to not empty completely or not empty at all. You are at increased risk for urinary retention if you are elderly, have a blockage in your bladder, have an enlarged prostate called benign prostatic hyperplasia (BPH), have bladder emptying problems from diabetes, or are taking higher doses of COBENFY. Urinary retention may increase your risk for getting a urinary tract infection. Call your healthcare provider or get emergency help right away if you get any signs or symptoms of urinary retention during treatment with COBENFY, including:
    • difficulty urinating
    • urination in a weak stream or drips
    • urinating frequently
    • full bladder and difficulty emptying your bladder
    • pain when you urinate
  • Risks in people with liver problems. See “Do not take COBENFY if you:” It is not recommended that people with mild liver problems (impairment) take COBENFY because they have an increased risk of getting side effects from COBENFY. Your healthcare provider will check the liver enzyme levels in your blood before starting treatment and as needed during treatment with COBENFY. Tell your healthcare provider if you get any signs or symptoms of liver problems during treatment with COBENFY, including:
    • yellowing of your skin or the white part of your eyes
    • dark urine
    • pain and swelling in the upper right part of your stomach (abdomen)
    • stomach pain that spreads to your back or to below your right shoulder
    • itching
    • nausea or vomiting
    • loss of appetite
    • fever
    • chills
    • light colored stools
    • tiredness
  • Risks in people with bile duct and gallbladder problems (biliary disease). COBENFY may cause a blockage in your bile ducts that could lead to gallstones, pancreatitis, and increases in your liver enzymes. Your healthcare provider will check your liver enzyme and bilirubin levels in your blood before starting treatment and as needed during treatment with COBENFY. Tell your healthcare provider if you get any signs or symptoms of biliary disorders during treatment with COBENFY, including:
    • stomach upset or burning (dyspepsia)
    • nausea
    • vomiting
    • pain in the upper right part of your stomach
  • Slow emptying of your stomach (decreased gastrointestinal motility). See “Do not take COBENFY if you:” You are at increased risk for getting decreased gastrointestinal motility if you have ulcerative colitis, already have problems with slow stomach emptying, and have myasthenia gravis. Tell your healthcare provider if you get any signs and symptoms of decreased gastrointestinal motility during treatment with COBENFY, including:
    • constipation
    • vomiting
    • nausea
    • stomach (abdominal) bloating
    • stomach (abdominal) pain
    • a feeling of fullness after eating just a few bites
    • acid reflux
  • Serious allergic reactions (angioedema). Angioedema may happen during treatment with COBENFY and can be life threatening. Stop taking COBENFY and call your healthcare provider or get emergency help right away if you get any of the following signs or symptoms of a serious allergic reaction during treatment with COBENFY, including:
    • hives
    • swelling of your face, lips, mouth, or tongue
    • swelling of your throat
    • hoarseness or difficulty speaking
    • breathing problems
  • An eye problem called narrow-angle glaucoma. See “Do not take COBENFY if you:” If you already have narrow angles in your eyes, COBENFY may cause a sudden attack (acute angle closure) of glaucoma. Tell your healthcare provider if you get any signs or symptoms of narrow-angle glaucoma during treatment with COBENFY, including:
    • red eyes
    • blurred vision
    • seeing halos or bright colors around lights
    • eye pain or discomfort
    • nausea or vomiting
    • severe headache
  • Increases in heart rate. COBENFY may increase your heart (pulse) rate. Your healthcare provider should check your heart rate before you start treatment and during treatment as needed. Tell your healthcare provider if you get a racing or pounding feeling in your chest during treatment with COBENFY.
  • Side effects in people with kidney problems. People with kidney problems may have an increased risk of getting dry mouth, constipation, stomach upset or burning, urinary tract infection, and urinary retention during treatment with COBENFY.
  • Central nervous system problems. See “What should I avoid while taking COBENFY?”

The most common side effects of COBENFY include:

  • nausea
  • stomach upset or burning (dyspepsia)
  • constipation
  • vomiting
  • high blood pressure
  • stomach (abdominal) pain
  • diarrhea
  • increased heart rate
  • dizziness
  • heartburn (gastrointestinal reflux disease)

Your healthcare provider may lower your dose or stop treatment with COBENFY if you get certain side effects.

These are not all of the possible side effects of COBENFY.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.